Key result
Impella CP with alpha-blockers and fluids stabilizes hemodynamics as a bridge to adrenalectomy in pheochromocytoma crisis.
Why the study?
Therapeutic strategies utilizing mechanical circulatory support in patients with pheochromocytoma-related cardiogenic shock remain unestablished.
Does percutaneous left ventricular assist device support improve outcomes in a patient with pheochromocytoma crisis and cardiogenic shock?
Case Report (n=1)
Does percutaneous left ventricular assist device support improve outcomes in a patient with pheochromocytoma crisis and cardiogenic shock?
Impella-supported medical management may serve as an effective bridge to surgery in patients with pheochromocytoma crisis complicated by cardiogenic shock.
May support Impella as bridge in pheochromocytoma crisis shock; hypothesis-generating, prospective data needed before practice change.
Therapeutic strategy utilizing mechanical circulatory supports in patients with pheochromocytoma-related cardiogenic shock remains unestablished. We had a 51-year-old man with acute decompensated heart failure due to pheochromocytoma crisis. He received a percutaneous left ventricular assist device-supported alpha-blocker and intensive fluid infusion therapy, which ameliorated impaired end-organ dysfunction, maintaining hemodynamics and achieving cardiac recovery, followed by the successfully scheduled adrenalectomy. Early suspicion of pheochromocytoma and Impella-supported disease-specific medical management might be a promising bridge to surgery strategy.
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Nakamura et al. (2022) conducted a case report in Pheochromocytoma crisis with cardiogenic shock (n=1). Percutaneous left ventricular assist device (Impella CP) and alpha-blocker was evaluated on Hemodynamic stabilization and cardiac recovery. Impella CP support combined with an alpha-blocker and intravenous fluid administration successfully stabilized hemodynamics and served as a bridge to elective adrenalectomy in a patient with pheochromocytoma crisis.
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