Key result
Valve-sparing root replacement shows excellent survival but a ~26% subsequent AVR rate due to degeneration.
Why the study?
Aortic root dilatation and aortic insufficiency occur in young patients with prior conotruncal defect surgery, Ross procedure, and connective tissue disease, but outcomes of valve-sparing aortic root replacement by congenital heart surgeons needed evaluation.
What are the long-term survival and reintervention outcomes of valve-sparing aortic root replacement performed by congenital heart surgeons in young patients?
Observational (n=49)
No
What are the long-term survival and reintervention outcomes of valve-sparing aortic root replacement performed by congenital heart surgeons in young patients?
Valve-sparing aortic root replacement can be safely performed by congenital heart surgeons with excellent survival, though valve degeneration requiring reintervention remains a significant concern.
Supports safe performance by congenital surgeons; leaves open durability versus alternatives in young patients.
Background Aortic root dilatation and aortic insufficiency can occur in patients with prior conotruncal defect surgery, the Ross procedure, and connective tissue disease (CTD). Valve-sparing aortic root replacement (VSRR) is an excellent choice for these young patients. We present the outcomes of young patients undergoing VSRR by congenital heart surgeons at a single center. Methods A single center retrospective chart review from April 2008 – April 2021 was performed. Patients with aortic root and valve pathology who underwent VSRR were identified. A total of 49 patients were identified by using the hospital surgical database. Three VSRR techniques were utilized during the study period; aortic valve-sparing root remodeling (Group 1, 7 patients), aortic valve-sparing root reimplantation (Group 2, 32 patients), and a modified root remodeling procedure utilizing a geometric annuloplasty ring (Group 3, 10 patients). Patient characteristics, post-VSRR echocardiogram studies and need for intervention, and survival were analyzed. Results Long-term survival after VSRR is excellent with only one death related to cardiac causes. Valve degeneration remains a concern with 13 patients (26%) requiring subsequent aortic valve replacement over the study period. Risk factors for aortic valve reintervention were the aortic root remodeling technique, mild or greater immediate post-operative aortic insufficiency and higher post-operative mitral insufficiency. Follow-up was significantly longer in Group 1 patients compared to Groups 2 and 3. Conclusions Valve-sparing aortic root replacement is safely performed by congenital heart surgeons in a heterogeneous patient population. Valve degeneration remains a concern and greater than trivial post-operative aortic insufficiency should prompt further attempts at valve repair or replacement.
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Hobbs et al. (2022) conducted an observational in Aortic root and valve pathology (n=49). Valve-sparing aortic root replacement was evaluated on Subsequent aortic valve replacement. Valve-sparing aortic root replacement resulted in excellent survival (1 cardiac death), but 26% of patients required subsequent aortic valve replacement due to valve degeneration.
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