Key result
Patient with uncorrected pentalogy of Fallot successfully completes pregnancy despite early delivery for fetal distress.
Why the study?
Patients with pentalogy of Fallot have a poor prognosis without reparative surgery early in life, making uncorrected survival and pregnancy uncommon.
Case Report (n=1)
This case demonstrates that successful pregnancy is possible in patients with uncorrected pentalogy of Fallot, highlighting the importance of accurate multimodality imaging for diagnosis.
Supports feasibility in uncorrected pentalogy of Fallot pregnancies; leaves open need for registry data to guide counseling.
Pentalogy of Fallot (PoF) is a congenital heart disease comprising tetralogy of Fallot plus an atrial septal defect (ASD). Patients are diagnosed early in life and submitted to reparative surgery. Without it, the prognosis is poor. This female patient, initially diagnosed with transposition of great arteries (TGA), ASD and a ventricular septal defect, got pregnant at 26 years old and had an early delivery due to fetal distress. She resumed follow-up, and her last echocardiogram put in doubt the diagnosis of TGA. Cardiac CT then revealed a PoF as well as pulmonary arteriovenous fistulas and a persistent left superior vena cava.
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Silveira et al. (2023) conducted a case report in Pentalogy of Fallot (n=1). Pregnancy was evaluated. A 26-year-old female with uncorrected pentalogy of Fallot successfully completed a pregnancy despite early delivery for fetal distress.
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