Key result
TNF-alpha and IFN-gamma mediate inflammatory processes impacting glial cells in MS and AIDS dementia.
Population
Glial cells in the central nervous system, specifically in the context of neurologic disorders such as…
Design
Review
Authors
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Should not yet alter MS or AIDS dementia care; leaves open glial cytokine targeting for future trials.
This review highlights the role of cytokine-mediated signaling pathways in glial cells and their contribution to the progression of neurologic disorders like MS and AIDS dementia complex.
Benveniste et al. (1995) conducted a review in Neurologic disorders (e.g., multiple sclerosis, AIDS dementia complex). TNF-alpha and IFN-gamma was evaluated. This review highlights the biological roles of TNF-alpha and IFN-gamma in mediating inflammatory processes and their impact on glial cells in neurologic disorders like MS and AIDS dementia complex.
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