Key result
Vitamin D <20 ng/ml linked to higher total cholesterol and LDL-C in obese children.
Why the study?
Vitamin D deficiency is reported in obese children and is associated with dyslipidemia and increased cardiovascular risk in adulthood.
Is Vitamin D insufficiency associated with an unfavorable lipid profile in obese children?
Population
120 obese pediatric subjects
Comparison
25OHD <20 ng/ml (Group A) vs 25OHD >20 ng/ml (Group B)
Design
Observational study
Authors
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May support lipid monitoring in obese children with low vitamin D; hypothesis-generating for supplementation trials.
Observational (n=120)
Is Vitamin D insufficiency associated with an unfavorable lipid profile in obese children?
p-value: p=0.017
Vitamin D insufficiency in obese children is associated with an unfavorable lipid profile, including elevated total cholesterol and LDL-C.
Rusconi et al. (2015) conducted an observational in Obesity (n=120). Vitamin D (25OHD) <20 ng/ml vs. Vitamin D (25OHD) >20 ng/ml was evaluated on Total cholesterol (TC) (p=0.017). Vitamin D levels <20 ng/ml in obese children were associated with elevated total cholesterol (p=0.017) and LDL-C (p=0.045) compared to levels >20 ng/ml.
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