What question did this study set out to answer?

To evaluate adherence levels to topical corticosteroids (TCS) and identify the clinical and psychological predictors of adherence among caregivers of children with atopic eczema.

May 1, 2025Patient Preference and AdherenceOpen Access

Predictors of Topical Corticosteroid Adherence Among Caregivers of Children with Atopic Eczema

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Authors

NSNoraida Mohamed ShahUniversity Kebangsaan Malaysia Medical Centre WCWei Wen ChongNational University of Malaysia LSLatha SelvarajahSultan Ismail Specialist Hospital

Discussion

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Implication

Cross-sectional study uncovers predictors of topical corticosteroid adherence among caregivers of children with eczema, suggesting that addressing steroid phobia improves treatment compliance.

Key Points

To evaluate adherence levels to topical corticosteroids (TCS) and identify the clinical and psychological predictors of adherence among caregivers of children with atopic eczema.
Recruited 121 caregivers of pediatric atopic eczema patients using TCS within the prior three months from dermatology clinics at two major hospitals.
Administered self-reported surveys capturing eczema severity, TCS phobia using the TOPICOP© instrument, and treatment adherence using a 12-item medication adherence scale.
Identified significant independent predictors of caregiver adherence using multiple linear regression analysis.
Caregivers demonstrated a mean adherence score of 48.5 (SD ± 6.6; maximum score of 60) and a mean global TOPICOP© phobia score of 25.4% (SD ± 14.5).
Severe eczema (B = 4.330, 95% CI 1.907 to 6.754, p < 0.001) and caregiver unfamiliarity with the medication name (B = 6.922, 95% CI 2.126 to 11.718, p < 0.05) positively predicted adherence.
Topical corticosteroid phobia served as a significant negative predictor of treatment adherence (B = -0.300, 95% CI -0.449 to -0.510, p < 0.001).

Cite This Study

Shah et al. (2025) studied this question.

synapsesocial.com/papers/6aa87a336d421d42e8f33719 https://doi.org/10.2147/ppa.s498527

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Implication

Cross-sectional study uncovers predictors of topical corticosteroid adherence among caregivers of children with eczema, suggesting that addressing steroid phobia improves treatment compliance.