This study explores the current state and future prospects of accelerating crop resistance trait improvement through Genome-Wide Association Studies (GWAS) strategies. With the rapid development of high-throughput sequencing technology and bioinformatics, GWAS has emerged as a powerful tool for linking DNA variations to important crop traits. This research particularly emphasizes the strategies for integrating multi-omics data, as well as the application of precision breeding and gene editing technologies based on GWAS findings, offering new directions and strategies for the improvement of crop resistance traits. Additionally, the emergence of methods such as Transcriptome-Wide Association Studies (TWAS) provides robust tools for identifying genes associated with complex traits, suggesting a more comprehensive understanding of genomic regulation and genetically regulated genes in the future. These advancements not only propel the scientific research of crop genetic improvement but also provide a solid scientific foundation for the sustainable development of crop production and food safety.
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Wenzhong Huang (2024) studied this question.
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