Caffeine and Autosomal Dominant Polycystic Kidney Disease

A recent long-term prospective study has demonstrated that coffee consumption by patients with autosomal dominant polycystic kidney disease (ADPKD) does not have a detrimental effect on kidney size or estimated glomerular filtration rate. We suggest that caffeine may, however, have a hypertensive effect in some ADPKD patients. Further research is needed before we can definitively state that caffeinated coffee consumption is harmless in ADPKD patients.