Key result
Non-atherosclerotic coronary pathologies like arteritis and dissection cause sudden cardiac death in four cases.
Case Report (n=4)
No
Non-atherosclerotic coronary diseases, such as arteritis, dissection, and fibrosis, are important, potentially unrecognized causes of sudden cardiac death that require careful clinical and pathological evaluation.
Non-atherosclerotic coronary disease merits consideration in SCD; case reports leave open prevalence and detection strategies.
Coronary atherosclerosis is responsible for >50% of all cases of sudden death and for 90% of sudden coronary death. Four cases encountered in routine autopsy evaluation at our institute in 2004 in which non-atherosclerotic coronary pathology was responsible for sudden cardiac death are reported. The cases of a 31-year-old man with epicardial coronary arteritis, a 57-year-old man with intramyocardial vasculitis, a 45-year-old woman with spontaneous coronary dissection and a 50-year-old man with vascular fibrosis are described. Searching for non-atherosclerotic coronary disease is relevant for both the clinician and the pathologist to prevent coronary causes of sudden death going unrecognised.
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De‐Giorgio et al. (2007) conducted a case report in Sudden cardiac death (n=4). Non-atherosclerotic coronary pathology was evaluated on Sudden cardiac death. Four cases of sudden cardiac death were caused by non-atherosclerotic coronary pathology, including epicardial coronary arteritis, intramyocardial vasculitis, spontaneous dissection, and fibrosis.
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