Key result
Endocardial RF ablation during valve surgery plus amiodarone shows ~88% sinus rhythm at six months.
Why the study?
Does endocardial RF ablation combined with amiodarone restore sinus rhythm in patients with permanent atrial fibrillation undergoing heart valve surgery?
Observational (n=29)
Does endocardial RF ablation combined with amiodarone restore sinus rhythm in patients with permanent atrial fibrillation undergoing heart valve surgery?
Endocardial RF ablation combined with 3 months of amiodarone during heart valve surgery effectively restores sinus rhythm at 6 months, particularly in patients with smaller left atrial diameters.
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Hypothesis-generating for combined ablation and amiodarone in valve surgery AF; randomized trials needed before adoption.
Geidel et al. (2003) conducted an observational in Permanent atrial fibrillation (n=29). Endocardial radiofrequency ablation and amiodarone was evaluated on Sinus rhythm at 6 months. Endocardial radiofrequency ablation during heart valve surgery followed by 3 months of amiodarone resulted in 87.5% of evaluated patients being in sinus rhythm at 6 months.
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