Key result
Postoperative SOFA score predicts in-hospital mortality after isolated CABG, linked to ~104% higher odds.
Why the study?
Mortality after CABG is associated with underlying disease and surgical factors overlooked in preoperative prognostic models, and the accuracy of SOFA and APACHE II scores for predicting mortality after CABG was investigated.
Do the Sequential Organ Failure Assessment (SOFA) and APACHE II scores predict in-hospital mortality in patients who underwent isolated CABG?
Observational (n=483)
No
Do the Sequential Organ Failure Assessment (SOFA) and APACHE II scores predict in-hospital mortality in patients who underwent isolated CABG?
The SOFA score is an independent predictor of in-hospital mortality following isolated CABG and may be useful for postoperative risk stratification.
BACKGROUND: Mortality after coronary artery bypass grafting (CABG) is generally associated with underlying disease and surgical factors overlooked in preoperative prognostic models. Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are widely used in intensive care units for outcome prediction. This study investigated the accuracy of these models in predicting mortality. METHODS: Between January 2010 and April 2013, 483 patients who underwent isolated CABG were enrolled. The clinical characteristics, outcomes, and prognostic model scores of the patients were collected. Discrimination was assessed using the area under the curve approach. RESULTS: Both SOFA and APACHE II scores were effective for predicting in-hospital mortality. Among the organ systems examined in the SOFA, the cardiac and renal systems were the strongest predictors of CABG mortality. Multivariate analysis identified only the SOFA score as being an independent risk factor for mortality. CONCLUSION: In summary, the SOFA score can be used to accurately identify mortality after isolated CABG.
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Chang et al. (2017) conducted an observational in Coronary artery bypass grafting (CABG) (n=483). Sequential Organ Failure Assessment (SOFA) score was evaluated on In-hospital mortality (OR 2.036, 95% CI 1.685-2.460, p=<0.001). The postoperative SOFA score accurately predicted in-hospital mortality after isolated CABG, with an area under the curve of 0.912 and an independent odds ratio of 2.036 for mortality.
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