Key result
Novel in vitro method identifies high mechanical stress in bioprosthetic valve upper leaflet edges and bellies.
Why the study?
Estimating local and global mechanical stress on bioprosthetic valve leaflets is important for better understanding valve durability.
A novel in vitro/in silico method successfully quantifies mechanical stress on bioprosthetic valve leaflets, identifying high-stress regions that may impact valve durability.
May guide bioprosthetic valve optimization to mitigate leaflet stress; leaves open clinical translation to reduced structural valve deterioration.
An original in vitro/in silico method was developed to estimate the local and global mechanical stress applied on the bioprosthetic valve leaflet, which can be important for better understanding of the valve durability. A non-contact system based on stereophotogammetry and digital image correlation enabled filming and studying the valve leaflet movement frame by frame and performing three-dimensional analysis. The deformation was applied in a finite element model in order to calculate the local mechanical stress applied. High stress regions were primarily observed in the upper leaflet edge and belly and to a lesser extent at the free leaflet edge.
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Stanová et al. (2019) studied Bioprosthetic valve leaflet mechanical stress. Stereophotogammetry and digital image correlation with finite element modeling was evaluated on Local and global mechanical stress applied on the bioprosthetic valve leaflet. A novel in vitro/in silico method using stereophotogammetry and digital image correlation identified high mechanical stress regions primarily in the upper leaflet edge and belly of bioprosthetic valves.
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