Key result
Intravenous dipyridamole-handgrip stress for PET imaging is linked to rare acute MI from LAD occlusion.
Why the study?
Complications of intravenous dipyridamole stress for rubidium-82 PET imaging are rare, with limited reports of acute myocardial infarction following this procedure.
Case Report (n=1)
No
This case highlights the rare but severe risk of acute myocardial infarction during intravenous dipyridamole stress testing, emphasizing the need for vigilant observation.
Rare AMI during dipyridamole-handgrip Rb-82 PET warrants vigilance; leaves open whether protocol changes are needed.
This report describes the occurrence of chest pain and electrocardiographic features of acute myocardial infarction following intravenous dipyridamole-handgrip stress. Myocardial perfusion imaging (Rb-82 PET) demonstrated a stress-induced perfusion defect. Following failure to respond to medical therapy, urgent cardiac catheterization demonstrated total occlusion of the left anterior descending coronary artery. The vessel was revascularized, with limitation of myocardial damage evidenced by failure to develop anterior Q waves and only modest elevation of cardiac enzyme levels. Complications of intravenous dipyridamole stress are rare, this case constituting the first major problem in over 500 such procedures at this institution. However, this experience demonstrates the importance of vigilant observation during the performance of this technique.
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Marwick et al. (1990) conducted a case report in Acute myocardial infarction (n=1). Intravenous dipyridamole-handgrip stress was evaluated on Acute myocardial infarction. Intravenous dipyridamole-handgrip stress for Rb-82 PET imaging was associated with a rare case of acute myocardial infarction due to total occlusion of the left anterior descending coronary artery.
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