Answers are grounded in this paper and cite their sources.
The polymyxins are a group of antibiotics which were first isolated from a spore-bearing soil bacillus, Bacillus polymyxa, in 1947. Colistin, also known as polymyxin E, was introduced into clinical practice over 50 years ago. Although it has remained available for use since then, it was largely shelved in the 1970s with the discovery of antibiotics that were equally or more effective but considered less toxic. 1 (Full text available online at www.medpharm.tandfonline.com/ojid ) South Afr J Infect Dis 2016; DOI: 10.1080/23120053.2016.1151157
No takes yet. Share an insight, caveat, or question.
Jennifer Coetzee (2016) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: