Key result
Transcervical excision and adjuvant radiotherapy successfully treat a rare parapharyngeal synovial sarcoma.
Case Report (n=1)
No
This case report highlights the rare presentation of synovial sarcoma in the parapharyngeal space and the utility of FISH for diagnosis.
May guide individualized multimodal care for rare parapharyngeal sarcomas; leaves open prospective validation of optimal sequencing.
Synovial sarcoma is a rare soft tissue sarcoma of the head and neck region involving the parapharyngeal space. The diagnosis of synovial sarcoma can be very challenging to the pathologists. We present a rare case of parapharyngeal synovial sarcoma in a young female patient who had a two-month history of left cervical intumescent mass at level II. The fine needle aspiration cytology of the mass was proved inconclusive. Transcervical excision of the mass was performed and the first case of parapharyngeal sarcoma was identified in our center by fluorescence in situ hybridization (FISH) technique. Repeat imaging revealed residual tumor. The patient successfully underwent a second excision of the residual tumor and received adjuvant radiotherapy.
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Ami et al. (2010) conducted a case report in Synovial sarcoma (parapharyngeal mass) (n=1). Transcervical excision and adjuvant radiotherapy was evaluated on Diagnosis and treatment outcome. Transcervical excision followed by a second excision for residual tumor and adjuvant radiotherapy successfully treated a rare parapharyngeal synovial sarcoma in a young female patient.
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