Why the study?
Pulmonary arterial hypertension is a rare but severe complication following neonatal arterial switch operation for transposition of the great arteries, where early diagnosis and aggressive therapy may improve survival.
Does vasodilator therapy improve clinical response in a pediatric patient with PAH following neonatal arterial switch operation for transposition of the great arteries?
Case Report (n=1)
Does vasodilator therapy improve clinical response in a pediatric patient with PAH following neonatal arterial switch operation for transposition of the great arteries?
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Vasodilator therapy may be effective for managing pulmonary arterial hypertension developing as a late complication after neonatal arterial switch operation for transposition of the great arteries.
Pulmonary arterial hypertension (PAH) is a rare but severe complication that should be investigated in patients diagnosed with transposition of the great arteries who have undergone neonatal arterial switch operation. Early diagnosis and aggressive combination therapy for PAH could help to improve survival in these patients. We report a favorable clinical response 6 months after the initiation of vasodilator therapy in a pediatric case with transposition of the great arteries, successfully repaired in the neonatal period, who developed pulmonary arterial hypertension at the age of 5 years.
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Şuteu et al. (2020) conducted a case report in Pulmonary arterial hypertension after arterial switch operation for transposition of the great arteries (n=1). Bosentan and sildenafil was evaluated on 6-minute walk test distance.
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