Key result
Transposition of the great arteries was associated with spontaneous VSD closure in ~20% of patients, and pulmonary stenosis in 28% of those with an intact ventricular septum and 50% with a VSD.
Population
65 patients with transposition of the great arteries
Design
Cohort
Authors
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May inform surveillance for spontaneous closure and PS in TGA; leaves open effects on timing of intervention and long-term outcomes.
Observational (n=65)
In patients with transposition of the great arteries, spontaneous ventricular septal defect closure occurs in about 20%, while pulmonary stenosis and pulmonary artery hypertension are common and vary based on ventricular septum status.
Plauth et al. (1970) conducted an observational in Transposition of the great arteries (n=65). Transposition of the great arteries was evaluated on Hemodynamic changes and defect status. Transposition of the great arteries was associated with spontaneous VSD closure in ~20% of patients, and pulmonary stenosis in 28% of those with an intact ventricular septum and 50% with a VSD.
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