Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes

Peng Du; Uma M. Viswanathan; Khairan Khairan; Tomislav Burić; Nathaniel Edward Bennett Saidu; Zhanjie Xu; Benjamin Hanf; Inga Bazukyan; Armen Trchоunian; Frank Hannemann; Ingolf Bernhardt; Torsten Burkholz; Britta Diesel; Alexandra K. Kiemer; Karl‐Herbert Schäfer; Mathias Montenarh; Gilbert Kirsch; Claus Jacob

doi:10.1039/c3md00204g

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Abstract

Several amphiphilic, chalcogen-based redox modulators have been synthesized which exhibit a widespread, yet in some instances also selective, biological activity which is most likely based on their ability to modulate the intracellular redox balance and to interact with cellular membranes and specific proteins.

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Du et al. (2013) studied this question.

synapsesocial.com/papers/6aa8df1eb17909331cd91846 https://doi.org/10.1039/c3md00204g

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Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes

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Abstract

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Cite This Study

Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes

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Abstract

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