Why the study?
The coexistence of paralytic poliomyelitis and an aggressive form of ALS in the same patient presents a diagnostic challenge and is rarely reported.
Case Report (n=1)
This case report highlights the unusual development of aggressive ALS in a patient with a history of childhood paralytic poliomyelitis.
Poliomyelitis, once a worldwide epidemic, is becoming increasingly rare owing to the introduction of the polio vaccine in the 1950s. It is estimated that the number of cases of polio has reduced by 99% since the Global Polio Eradication Initiative (GPEI) started in 1988. Amyotrophic lateral sclerosis (ALS) is another relatively uncommon condition which also affects anterior horn cells with debilitating neurological, and deadly, consequences. An unusual case of an aggressive form of ALS developing in a 72-year-old patient with paralytic poliomyelitis in childhood is presented. Her initial presentation was puzzling, and our approach to the diagnostic dilemma is discussed.
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Ebony S Gilbee (2013) conducted a case report in Amyotrophic lateral sclerosis (ALS) and paralytic poliomyelitis (n=1). Paralytic poliomyelitis in childhood was evaluated.
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