Key result
Higher triglyceride glucose index linked to ~126% higher odds of severe abdominal aortic calcification.
Why the study?
The study was conducted to investigate the relationship between the triglyceride glucose index and abdominal aortic calcification in people over 60 years old.
Is a higher triglyceride glucose index associated with severe abdominal aortic calcification in people over 60 years old?
Cross-Sectional (n=1,408)
Is a higher triglyceride glucose index associated with severe abdominal aortic calcification in people over 60 years old?
Higher triglyceride glucose index is significantly associated with severe abdominal aortic calcification in older adults.
TyG index should not yet inform calcification risk assessment; leaves open whether it adds value beyond established factors.
Background The association between triglyceride glucose (TYG) index and depression is unclear. We conducted this analysis to explore whether higher TYG index is associated with a higher odd of depression. Aims The objective was to investigate the relationship between TYG and abdominal aortic calcification (AAC) in people over 60 years old. Methods The National Health and Nutrition Examination Survey data were analyzed using logistic regression models to examine the independent association between TYG index and the Kauppila AAC-24 score. Results A total of 1,408 people took part in our study. Participants with higher TYG quartiles had higher AAC scores. SAAC was defined as a Kauppila score > 6, and the prevalence of SAAC was 17.0%. After adjusting for relevant covariates, the multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CI) for participants in the third and fourth quartiles were 1.970 (1.232–3.150, P = 0.005) and 2.261 (1.404–3.644, P < 0.001). Subgroup analyses indicated that the positive association between TYG and SAAC persisted across population subgroups. Conclusion Triglyceride glucose index was negatively correlated with SAAC in the elderly.
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Pan et al. (2023) conducted a cross-sectional in Severe abdominal aortic calcification (n=1,408). Triglyceride glucose (TYG) index vs. Lowest TYG index quartile was evaluated on Severe abdominal aortic calcification (SAAC) (OR 2.261, 95% CI 1.404-3.644, p=<0.001). A higher triglyceride glucose index was independently associated with increased odds of severe abdominal aortic calcification in older adults, with the highest quartile showing an OR of 2.261 compared to the lowest quartile.
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