In addition to azorellanol a new diterpenoid 7-deacetylazorellanol, has been isolated from the aerial parts oiLaretia acaulis (Cav.) Gill et Hook (Umbelliferae). Its structure was based on spectroscopic comparison with azorellanol and chemical grounds. Azorellanol and 7-deacetylazorellanol showed marked inhibitor activity against trophozoites of protozoan parasite Toxoplasma gondii. The 50 % inhibitory dose for azorellanol was calculated in 54 nM and for 7-deacetylazorellanol was 42 nM.
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Loyola et al. (2001) studied this question.
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