A hyperthermia system working at frequencies around 150 MHz is described. It is useful for a penetration depth of 3-4 cm in tumor and muscle tissue. The system includes a new type of inductive applicator giving a beam-like distribution in the tissue, a controllable surface cooling system, and multipoint temperature measurements. A phase I clinical study shows the efficacy of the system, but also the importance of temperature measurements at many points since, in general, the temperature gradients are large.
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Anderson et al. (1984) studied this question.
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