Key result
Obesity in COVID-19 ARDS is linked to AKI requiring RRT but not higher mortality.
Why the study?
Chronic conditions like obesity are linked to adverse outcomes in COVID-19 ARDS, but the relationship between BMI and outcomes in critically ill patients required evaluation.
Does obesity increase mortality and complications in critically ill patients with COVID-19 ARDS?
Comparison
Obesity (BMI >=30 kg/m 2) vs without obesity (BMI >18.5 up to 29.9 kg/m 2)
Design
Retrospective cohort study
Authors
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Obesity signals higher continuous RRT need in COVID-19 ARDS; leaves open independent mortality effect and requires prospective confirmation.
Cohort (n=108)
Does obesity increase mortality and complications in critically ill patients with COVID-19 ARDS?
p-value: p=0.056
In patients with COVID-19 ARDS, obesity is associated with a higher risk of AKI requiring RRT but not significantly higher overall mortality, though concurrent ischemic heart disease increases mortality risk.
Telang et al. (2024) conducted a cohort in COVID-19 acute respiratory distress syndrome (ARDS) (n=108). Obesity (BMI ≥30 kg/m2) vs. Without obesity (BMI >18.5 up to 29.9 kg/m2) was evaluated on Mortality, duration of mechanical ventilation, and length of ICU stay (p=0.056). In critically ill patients with COVID-19 ARDS, obesity was not associated with increased mortality (P=0.056) but was linked to a higher risk of acute kidney injury requiring renal replacement therapy (P=0.005).
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