C achexia in chronic heart failure (HF) is a major clinical problem that is still underestimated for its impact on morbidity, mortality, and healthcare expenditures.The pathophysiology of cardiac cachexia is characterized by a catabolic/ anabolic imbalance.An important player in the development of muscle wasting and cachexia in HF may be myostatin.
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Springer et al. (2010) studied this question.
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