Key result
Simultaneous QRS and ST-segment alternans highlights complex cardiac electrical phenomena unexplained by a single hypothesis.
Why the study?
The mechanisms underlying QRS- and ST-segment electrical alternans, especially their association with ischemic episodes and myocardial disease, remain imperfectly understood.
Case Report (n=1)
Highlights a rare case of simultaneous QRS- and ST-segment alternans, suggesting complex and multifactorial mechanisms for phasic cardiac electrical phenomena.
Answers are grounded in this paper and cite their sources.
Case report of simultaneous QRS- and ST-segment alternans suggests multifactorial mechanisms; leaves open single-hypothesis models for future study.
• A patient's condition was unique for having both QRS- and ST-segment alternans. The close association between ST-segment alternans and ischemic episodes is reproducible in an animal experimental study. Although such phenomena are usually associated with extensive myocardial disease, the postulated mechanism is far from perfected. It is more than likely that no single hypothesis will explain all types of phasic cardiac electrical phenomena. (Arch Intern Med1983;143:1052-1053)
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Tien Chu Cheng (1983) conducted a case report in QRS- and ST-segment alternans (n=1). QRS- and ST-segment alternans was evaluated. A unique case of simultaneous QRS- and ST-segment alternans demonstrated the complexity of phasic cardiac electrical phenomena, which likely cannot be explained by a single hypothesis.
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