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September 1, 1997Development

A dominant-negative form of Serrate acts as a general antagonist of Notch activation

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Authors

NHNeil A. HukriedeUniversity of PittsburghYGYi GuUniversity of AkronRFR.J. FlemingCLEARink (United States)

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Cite This Study

Hukriede et al. (1997) studied this question.

synapsesocial.com/papers/6aa8fc5a8270b7a97d6bf84ahttps://doi.org/10.1242/dev.124.17.3427
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila1997 · 146 citations
  2. 2Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing1995 · 411 citations
  3. 3Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc1996 · 315 citations
  4. 4Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo1995 · 71 citations