Key result
Open partial nephrectomy successfully treats a juxtaglomerular cell tumor, rapidly normalizing BP and potassium.
Case Report (n=1)
No
Nephron-sparing surgery (partial nephrectomy) is an effective treatment for reninoma, allowing recovery and preservation of renal function.
Supports partial nephrectomy for reninoma with preserved function; hypothesis-generating pending prospective data.
INTRODUCTION: The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension. CASE PRESENTATION: A 35-year-old African male patient referred to our institution, presenting with severe hypertension for 4 years. Renal magnetic resonance imaging showed a solid 9-mm lesion in the right upper pole cortex with high signal intensity on diffusion-weighted imaging, isointense on T2, and enhanced after contrast injection. The patient underwent an open right partial nephrectomy. The diagnosis of reninomas was confirmed by histopathological examination. CONCLUSION: Nephron-sparing surgery should be considered in patients with juxtaglomerular tumors. This technique allows prompt recovery with the preservation of significant renal function.
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Chaker et al. (2025) conducted a case report in Juxtaglomerular cell tumor (reninoma) (n=1). Open right partial nephrectomy was evaluated on Resolution of hypertension and hypokalemia. Open right partial nephrectomy successfully treated a 9-mm juxtaglomerular cell tumor, leading to rapid normalization of blood pressure and serum potassium levels with preserved renal function.
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