We report the case of a 67-year-old man who developed a pustular eruption, fever, neutrophilia and eosinophilia, following a short course of allopurinol. Toxic pustuloderma is an uncommon form of generalized pustular eruption with several characteristic clinical and pathological features. A number of drugs have been incriminated, but to our knowledge this is the first reported case of toxic pustuloderma occurring after the administration of allopurinol.
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Yu et al. (1993) studied this question.
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