What is the clinical evidence from this study?

Study design: Case Report. Population: Left atrial myxoma (n=1). Intervention: Surgical excision. Primary outcome: Hemodynamic stabilization and postoperative course.

What does this research mean for the field?

Atrial myxoma must be considered in the differential diagnosis of left atrial masses even in patients with prothrombotic conditions, and transesophageal echocardiography is essential for its accurate diagnosis and risk assessment. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe the clinical presentation, echocardiographic differentiation, and emergency surgical management of a left atrial myxoma initially misidentified as a thrombus.

September 15, 2026European Heart Journal SupplementsOpen Access

When a Suspected Thrombus Is Not a Thrombus: A Case of Left Atrial Myxoma With High Embolic Risk

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Key result

Urgent surgical excision of a left atrial myxoma mimicking a thrombus restores hemodynamic stability.

Population

1 51-year-old woman presenting with palpitations and hypotension, with a history of thrombocytosis of…

Design

Case_report

Authors

ANA NardoneOspedale Antonio Cardarelli LFL FalconeOspedale Antonio Cardarelli STS TestaOspedale Antonio Cardarelli

Discussion

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Implication

Incidental myxoma detection in palpitations warrants imaging vigilance; leaves open questions on screening in thrombocytosis.

Key Points

To describe the clinical presentation, echocardiographic differentiation, and emergency surgical management of a left atrial myxoma initially misidentified as a thrombus.
Clinical assessment of a 51-year-old woman presenting with palpitations, hypotension, and preexisting thrombocytosis using electrocardiography and transthoracic echocardiography.
Definitive anatomical and mobility assessment using transesophageal echocardiography, followed by urgent surgical resection and histopathological confirmation.
Transesophageal echocardiography revealed a 3.8 × 1.9 cm multilobulated, mobile mass attached to the interatrial septum that prolapsed into the left ventricle during diastole.
Histopathology confirmed a benign atrial myxoma following complete surgical excision, leading to immediate hemodynamic stabilization and an uneventful recovery.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 51-year-old woman presenting with palpitations and hypotension, found to have a left atrial myxoma.

Intervention

Transesophageal echocardiography followed by urgent surgical excision

Outcome

Hemodynamic stabilization and histological confirmation of atrial myxoma

Transesophageal echocardiography is critical for differentiating atrial myxoma from thrombus, especially in patients with prothrombotic conditions, to guide urgent surgical intervention.

Cite This Study

Nardone et al. (2026) conducted a case report in Left atrial myxoma (n=1). Surgical excision was evaluated on Hemodynamic stabilization and postoperative course. Urgent surgical excision of a left atrial myxoma, initially suspected to be a thrombus, led to hemodynamic stabilization and an uneventful postoperative course in a 51-year-old woman.

synapsesocial.com/papers/6aa9016aeed42882c1fc1863 https://doi.org/10.1093/eurheartjsupp/suag058.319

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When a Suspected Thrombus Is Not a Thrombus: A Case of Left Atrial Myxoma With High Embolic Risk

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

When a Suspected Thrombus Is Not a Thrombus: A Case of Left Atrial Myxoma With High Embolic Risk

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider