What is the clinical evidence from this study?

Study design: Case Report. Population: Myopericarditis (n=1). Intervention: Heart failure therapy and high-dose corticosteroids.

What does this research mean for the field?

Myopericarditis can present insidiously with atypical neurological symptoms such as a cardioembolic stroke, necessitating an integrated multimodality imaging approach for timely diagnosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe a rare case of eosinophilic infiltrative myopericarditis presenting atypically as an acute minor cardioembolic stroke and highlight the pathways for timely diagnosis and management.

September 15, 2026European Heart Journal Supplements

Myopericarditis: The Importance of Timely Identification for Optimal Clinical and Therapeutic Management

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Key result

HF therapy and corticosteroids achieve hemodynamic control in eosinophilic infiltrative myopericarditis following cardioembolic stroke.

Population

A 60-year-old man presenting with a minor stroke of cardioembolic etiology, with a medical history of…

Design

Case_report

Follow-up

six months

Authors

PLP De LucaOspedale Sant'Anna VSV SollazzoOspedale Sant'Anna ALA De LucaOspedale Sant'Anna

Discussion

Member takes

Implication

Eosinophilic myopericarditis may underlie unexplained LV thrombus and embolic stroke; leaves open systematic evaluation in infiltrative cardiomyopathies.

Key Points

To describe a rare case of eosinophilic infiltrative myopericarditis presenting atypically as an acute minor cardioembolic stroke and highlight the pathways for timely diagnosis and management.
Clinical, laboratory, and multimodality imaging workup of a 60-year-old male presenting with transient neurological deficits (right-sided weakness and dysarthria).
Diagnostic evaluations included brain CT, serial electrocardiograms, echocardiography, laboratory panels (cardiac troponins and complete blood counts), and coronary CT angiography.
Therapeutic intervention comprised heart failure pharmacotherapy and high-dose systemic corticosteroids, with hemodynamic follow-up conducted at 2 and 6 months post-discharge.
Brain CT and blood work identified suspected cardioembolic lesions alongside lymphocytosis and marked eosinophilic granulocytosis.
Echocardiography revealed left ventricular apical akinesia, an apical ventricular thrombus, mild non-tamponading pericardial effusion, and elevated cardiac troponin levels, while coronary CT angiography excluded obstructive coronary artery disease.
Treatment with high-dose corticosteroids and standard heart failure therapy led to successful clinical recovery, with sustained favorable hemodynamic control maintained at 2- and 6-month follow-up evaluations.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 60-year-old man presenting with a minor stroke of cardioembolic etiology caused by eosinophilic infiltrative myopericarditis.

Intervention

Heart failure therapy and high-dose corticosteroids

Outcome

Hemodynamic control and clinical improvement

Myopericarditis can present insidiously with neurological symptoms secondary to cardioembolic stroke, highlighting the importance of multimodality cardiovascular imaging in the diagnostic workup.

Cite This Study

Luca et al. (2026) conducted a case report in Myopericarditis (n=1). Heart failure therapy and high-dose corticosteroids was evaluated. A 60-year-old man with asymptomatic eosinophilic infiltrative myopericarditis presented with a cardioembolic stroke and achieved good hemodynamic control with heart failure therapy and corticosteroids.

synapsesocial.com/papers/6aa9016aeed42882c1fc189a https://doi.org/10.1093/eurheartjsupp/suag058.395

Topics

Myocarditis

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Implication

Eosinophilic myopericarditis may underlie unexplained LV thrombus and embolic stroke; leaves open systematic evaluation in infiltrative cardiomyopathies.

Myopericarditis: The Importance of Timely Identification for Optimal Clinical and Therapeutic Management

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Myopericarditis: The Importance of Timely Identification for Optimal Clinical and Therapeutic Management

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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