What is the clinical evidence from this study?

Study design: Case Report. Population: Biventricular Takotsubo Syndrome (n=1).

What does this research mean for the field?

Takotsubo syndrome can present atypically with biventricular involvement in elderly males in the absence of classical emotional triggers. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To document an atypical presentation of biventricular Takotsubo syndrome lacking classical emotional or physical triggers in an elderly male.

September 15, 2026European Heart Journal Supplements

An Atypical Case of Biventricular Takotsubo Syndrome in a Elderly Man

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Key result

Coronary vasospasm likely triggers atypical biventricular Takotsubo syndrome without classical emotional triggers.

Why the study?

Takotsubo syndrome involvement in male patients, especially of advanced age, remains underreported.

Population

An 86-year-old man presenting with acute chest pain

Design

Case report

Authors

DCD CaraceniAzienda Ospedaliero Universitaria Ospedali Riuniti ICI ConcettiAzienda Ospedaliero Universitaria Ospedali Riuniti ABA BontempoAzienda Ospedaliero Universitaria Ospedali Riuniti

Discussion

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Implication

May warrant expanded suspicion for atypical Takotsubo in trigger-negative cases; leaves open diagnostic criteria and prevalence.

Key Points

To document an atypical presentation of biventricular Takotsubo syndrome lacking classical emotional or physical triggers in an elderly male.
Evaluated an 86-year-old male presenting with acute chest pain and a history of chronic ischemic heart disease.
Performed diagnostic workup including serial electrocardiography, high-sensitivity troponin assays, coronary angiography, and transthoracic echocardiography.
Coronary angiography revealed non-culprit 50% to 60% LAD stenosis, while echocardiography demonstrated right ventricular apical akinesia and left ventricular apical hypokinesia.
High-sensitivity troponin was mildly elevated at 43 ng/L, followed by the appearance of diffuse T-wave inversions and marked QTc prolongation to 640 ms.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

An 86-year-old man with a history of chronic ischemic heart disease who presented with biventricular Takotsubo syndrome without classical emotional triggers.

This case illustrates an atypical presentation of biventricular Takotsubo syndrome in an elderly male without classical emotional triggers, highlighting the disease's wide clinical spectrum.

Cite This Study

Caraceni et al. (2026) conducted a case report in Biventricular Takotsubo Syndrome (n=1). An 86-year-old man presented with an atypical case of biventricular Takotsubo syndrome without classical emotional triggers, likely triggered by coronary vasospasm.

synapsesocial.com/papers/6aa9017deed42882c1fc1933 https://doi.org/10.1093/eurheartjsupp/suag058.475

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An Atypical Case of Biventricular Takotsubo Syndrome in a Elderly Man

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

An Atypical Case of Biventricular Takotsubo Syndrome in a Elderly Man

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

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