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September 15, 2026Journal of Cardiovascular ImagingOpen Access

Pulmonary hypertension in pregnancy: hemodynamic challenges, maternal risk, and multidisciplinary management

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Key result

Pregnancy in women with PH remains high-risk and demands individualized multidisciplinary peripartum care.

Why the study?

Pulmonary hypertension during pregnancy remains high risk because normal gestational cardiovascular adaptation can exceed right ventricular-pulmonary circulation reserve, with heterogeneous risks across PH phenotypes.

Population

Pregnant women with pulmonary hypertension

Design

Review

Authors

SCSung‐A ChangHeart Failure & Transplant

Discussion

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Implication

Supports multidisciplinary peripartum care with echocardiographic surveillance in pulmonary hypertension; leaves open standardized protocols for prospective validation.

Key Points

  • To review the hemodynamic stress, phenotype-specific maternal and fetal risks, delivery strategies, and multidisciplinary monitoring protocols for pulmonary hypertension during pregnancy.
  • Narrative review synthesizing pathophysiology, contemporary clinical outcomes, echocardiographic monitoring, and perioperative care protocols for pregnant individuals with pulmonary hypertension.
  • Normal gestational increases in plasma volume and cardiac output impose unsustainable pressure overload on the right ventricle due to fixed or elevated pulmonary vascular resistance.
  • The first 24 to 72 hours postpartum represents a critical period of hemodynamic stress driven by autotransfusion and extracellular fluid shifts, precipitating right ventricular failure, hypoxemia, or circulatory collapse.
  • Right ventricular dilatation causes adverse ventricular interdependence by shifting the interventricular septum leftward, reducing left ventricular filling, preload, and systemic output.

PICO

P
Population
Pulmonary hypertension in pregnancy

Pregnancy in women with pulmonary hypertension requires individualized risk assessment based on phenotype, disease severity, and right ventricular function, with intensive multidisciplinary monitoring particularly during delivery and the early postpartum period.

Cite This Study

Sung‐A Chang (2026) conducted a review in Pulmonary hypertension in pregnancy. Pregnancy in women with pulmonary hypertension remains a high-risk condition requiring individualized risk assessment, multidisciplinary care, and careful peripartum management.

synapsesocial.com/papers/6aa9017deed42882c1fc193dhttps://doi.org/10.1186/s44348-026-00096-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Eisenmengerʼs Syndrome and Pregnancy1979 · 235 citations
  2. 2N-terminal pro-B-type natriuretic peptide predicts cardiovascular complications in pregnant women with congenital heart disease2013 · 124 citations
  3. 3Pulmonary Hypertension in Pregnancy: Challenges and Solutions2022 · 30 citations
  4. 4Pulmonary Hypertension and Pregnancy2019 · 121 citations
  5. 5Pregnancy Considerations in the Multidisciplinary Care of Patients with Pulmonary Arterial Hypertension2022 · 23 citations