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To investigate the metabolism of riboflavin, [2-14 C]-riboflavin was administered orally to a rat. The urine pooled for 24h after administration was fractionated by paper and silica gel thin layer chromatographies using various solvent systems. Among the radioactive metabolites, riboflavinyl glucoside was found along with 7-carboxy lumichrome and 8-carboxy lumichrome. The radioactivity of riboflavinyl glucoside comprised about 6% of the total radioactivity excreted in the urine during 24h.
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Ohkawa et al. (1983) studied this question.
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