Systematic review reveals variable incidence trends and incomplete surveillance of non-melanoma skin cancer across European populations, highlighting the need for standardized registry tracking.
Background: Non-melanoma skin cancer (NMSC), principally basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), is incompletely captured by cancer surveillance. Objective: To synthesize European epidemiological evidence, with Poland considered in this context. Methods: PubMed/MEDLINE, Scopus, and Web of Science were searched for publications dated 1 January 2015–31 March 2026, supplemented by registry resources and reference-list searching. Additional eligibility checks during manuscript revision continued until 30 August 2026. The publication-date criterion was distinct from the observation periods of source data. Source-level methodological appraisal informed a descriptive synthesis. Results: The consolidated selection record comprised 198 records, 165 screened records, 61 full-text assessments, 37 full-text exclusions, and 24 included sources. Several registry-based studies reported increasing BCC or cSCC incidence in defined populations. Model-based age-standardized trends varied by geography, sex, age, and observation period. These results do not establish a uniform European increase. Polish estimates were affected by histological aggregation and incomplete ascertainment. Selected pandemic-period studies reported fewer diagnoses or changes in the treated case mix; these findings do not establish a Europe-wide decline in biological incidence or subsequent rebound. Conclusions: NMSC creates a substantial and incompletely measured European burden. Histology-specific registration, explicit multiple-primary counting rules, and improved outpatient capture are priorities for interpreting trends and planning care.
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