What does this research mean for the field?

Disseminated Klebsiella pneumoniae infection can present as diffuse subepithelial lesion-like elevations in the colon, mimicking malignant or infiltrative diseases. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To report a rare manifestation of disseminated Klebsiella pneumoniae infection presenting as multiple colonic subepithelial-like elevations that mimicked malignant disease.

September 15, 2026DEN OpenOpen Access

Disseminated Klebsiella pneumoniae Infection Mimicking Multiple Colonic Subepithelial Lesions: A Case Report

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To report a rare manifestation of disseminated Klebsiella pneumoniae infection presenting as multiple colonic subepithelial-like elevations that mimicked malignant disease.
Evaluated a 73-year-old male presenting with diarrhea, edema, and anemia via colonoscopy and endoscopic ultrasonography.
Conducted histopathological analysis, tissue cultures of colonic biopsies, and systemic diagnostic imaging to determine the primary source of infection.
Colonoscopy demonstrated numerous subepithelial lesion-like elevations from the cecum to rectum, with biopsy cultures identifying Klebsiella pneumoniae.
Systemic assessment revealed concurrent pacemaker lead infection, infective endocarditis, and pyogenic spondylitis.
Colonic elevations and systemic infection resolved following targeted antimicrobial therapy and cardiac device management.

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Implication

Case report reveals disseminated Klebsiella pneumoniae mimicking colonic subepithelial lesions in an older adult, highlighting bacterial infection as a differential for diffuse masses.

Cite This Study

Kobayashi et al. (2026) studied this question.

synapsesocial.com/papers/6aa913e49013453be30a228a https://doi.org/10.1002/deo2.70431

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Implication

Case report reveals disseminated Klebsiella pneumoniae mimicking colonic subepithelial lesions in an older adult, highlighting bacterial infection as a differential for diffuse masses.

Disseminated Klebsiella pneumoniae Infection Mimicking Multiple Colonic Subepithelial Lesions: A Case Report

Key Points

Discussion

Implication

Cite This Study

Disseminated Klebsiella pneumoniae Infection Mimicking Multiple Colonic Subepithelial Lesions: A Case Report

Key Points

Discussion

Implication

Cite This Study

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