Key result
Carl Creative PlateTrac improves programming ease, run time, and accuracy for volumes ≤1 μl versus competitors.
Why the study?
Several types of liquid handling equipment used in high throughput screening require comparison for programming ease, assay time, and dispensing accuracy.
Population
Protease screen and cell-based reporter gene assay model systems
Comparison
Carl Creative PlateTrac vs Matrix PlateMate vs Tomtec Quadra-96T vs Zymark RapidPlate-96
Design
Comparative evaluation of automated pipettors in HTS
Authors
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May enhance lab assay efficiency; leaves open generalizability across protocols and platforms.
Different automated liquid handling systems offer distinct advantages for high-throughput screening, with some excelling in precision at low volumes and others in complex multi-step tasks.
Stevens et al. (1998) studied High Throughput Screening. Carl Creative PlateTrac vs. Matrix PlateMate, Tomtec Quadra-96T, and Zymark RapidPlate-96 was evaluated on Ease of programming, assay-completion time, accuracy and precision of liquid dispensing, and low-volume pipetting. The Carl Creative PlateTrac demonstrated advantages in ease of programming, reduced assay run time, and increased accuracy for volumes ≤1 μl compared to other liquid handling equipment.