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April 11, 2000Proceedings of the National Academy of SciencesOpen Access

High metastatic potential in mice inheriting a targeted p53 missense mutation

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Authors

GLGeng LiuMontreal Neurological Institute and HospitalTMTimothy J. McDonnellThe University of Texas MD Anderson Cancer CenterRLRoberto Montes de Oca LunaCenter for the Study of Social Policy

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Liu et al. (2000) studied this question.

synapsesocial.com/papers/6aa91d214ecef0db9504e4f5https://doi.org/10.1073/pnas.97.8.4174
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.1989 · 384 citations
  2. 2Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors1998 · 389 citations
  3. 3p53 increases experimental metastatic capacity of murine carcinoma cells.1988 · 61 citations