Phytochemical analysis uncovers kavalactones and a novel benzoic acid derivative in Piper fuligineum leaves, expanding the chemical diversity of Piperaceae.
The known kavalactones (E)-4-methoxy-6-styryl-2H-pyran-2-one, 4-methoxy-6-(3-phenyloxiran-2-yl)-2H-pyran-2-one, 6-(1,2-dihydroxy-2-phenylethyl)-4-methoxy-2H-pyran-2-one, the three benzoic acid derivatives methyl-4-methoxy-3-(3'-methyl-2'-butenyl)benzoate and methyl 2,2-dimethyl-4-oxochroman-6-carboxylate, and a new methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate were isolated from the ethanolic extract of Piper fuligineum.The structures of these compounds were determined by using a combination of spectroscopic methods, including 1D-and 2D-nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry.This is the first report of the chemical study of P. fuligineum, and the methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate is described as a new natural product.
No takes yet. Share an insight, caveat, or question.
Mazzeu et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: