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June 1, 2017Translational Lung Cancer ResearchOpen Access

Targeting the epigenome in malignant pleural mesothelioma

Kaitlin C. McLoughlin Andrew S. Kaufman David S. Schrump

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Abstract

Malignant pleural mesotheliomas (MPM) are notoriously refractory to conventional treatment modalities. Recent insights regarding epigenetic alterations in MPM provide the preclinical rationale for the evaluation of novel combinatorial regimens targeting the epigenome in these neoplasms.

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McLoughlin et al. (2017) studied this question.

synapsesocial.com/papers/6aa920ad26fc75fc2acdbf57 https://doi.org/10.21037/tlcr.2017.06.06

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