Key result
Coronary artery anomalies are mostly benign variants linked to a ~10% adverse event rate over 36 months.
Why the study?
Certain high-risk coronary artery anomalies predispose patients to ischemia, arrhythmias, or sudden cardiac death, requiring characterization of prevalence, imaging features, management, and outcomes.
Population
133 patients with coronary artery anomalies identified from 8,000 patients undergoing coronary angiography
Comparison
Medical therapy vs PCI vs surgery
Design
Single-centre retrospective cohort study
Follow-up
Median 36-month
Authors
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Supports conservative management for most anomalies on angiography; leaves open prospective validation of risk stratification for malignant variants.
Observational (n=133)
No
In adults with coronary artery anomalies, most variants are benign and safely managed medically, while high-risk anatomies like interarterial courses warrant surgical correction to prevent adverse events.
Rajesh Thachathodiyl (2025) conducted an observational in Coronary artery anomalies (n=133). Coronary artery anomalies was evaluated on Adverse events (myocardial infarction, revascularization, or cardiac death). Coronary artery anomalies were identified in 1.6% of patients undergoing angiography, with most cases being benign variants managed conservatively and an overall adverse event rate of 10% over 36 months.
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