Key result
3D aortic reconstruction software yields new quantitative parameters characterizing normal aortas and aneurysm-induced shape deviations.
Why the study?
General laws of change in dynamic aortic geometry related to swirling blood flow hydrodynamics have not been properly studied to guide disease correction.
Observational
The study introduces new quantitative parameters based on 3D reconstruction to formalize the dynamic geometry and pathological remodeling of the aortic flow channel.
Analysis of the properties of the aorta was carried out by numerous researchers using several parameters. However, the general laws of change in the dynamic geometry of the aortic flow channel in connection with the hydrodynamics of the swirling blood flow have not been studied properly. Therefore, at present, attempts to correct various diseases are carried out based on the location of the aneurysm, and not in accordance with the general patterns of changes in the dynamic geometry of the entire aortic channel. For a proper understanding of the aortic flow channel remodeling mechanisms, it is necessary to determine the quantitative parameters that formalize the geometry of this channel. The geometric shape of the aorta primarily depends on the hydrodynamics of the flow inside the aortic flow channel, which is the only source of force impact on its walls. The main result of the present study was that we obtained the new quantitative parameters that characterize the normal aorta and the degree of its shape deviations caused by pathological changes of the aortic duct. These parameters were calculated based on the software processing of the three-dimensional aortic reconstruction in normal conditions and in the case of differently localized aortic aneurysm.
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Talygin et al. (2022) conducted an observational in Aortic aneurysm. Three-dimensional aortic reconstruction vs. Normal aorta was evaluated on Quantitative parameters characterizing the normal aorta and shape deviations. Software processing of 3D aortic reconstructions yielded new quantitative parameters characterizing the normal aorta and shape deviations caused by differently localized aortic aneurysms.
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