Key result
3D computational fluid dynamics modeling of a simulated abdominal aortic aneurysm demonstrated increased velocity at the angular neck and focalized high wall shear stress at the top and bottom.
Why the study?
Mechanical parameters contribute to abdominal aortic aneurysm rupture, and evaluating these parameters could improve clinical treatment. The study aimed to develop and demonstrate a methodology to analyze the fluid dynamics causing wall stress distribution using 3D geometry and a biomechanical model.
Computational fluid dynamics modeling of abdominal aortic aneurysms can identify focal points of high wall shear stress, potentially aiding in case-specific prediction of rupture risk.
May enhance AAA rupture risk stratification via fluid dynamics modeling; leaves open prospective validation before clinical adoption.
BACKGROUND: Besides biological factors, abdominal aortic aneurysm rupture is also caused by mechanical parameters, which are constantly affecting the wall's tissue due to their abnormal values. The ability to evaluate these parameters could vastly improve the clinical treatment of patients with abdominal aortic aneurysms. The objective of this study was to develop and demonstrate a methodology to analyze the fluid dynamics that cause the wall stress distribution in abdominal aortic aneurysms, using accurate 3D geometry and a realistic, nonlinear, elastic biomechanical model using a computer-aided software. METHODS: The geometry of the abdominal aortic aneurysm; was constructed on a 3D scale using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA). Due to the complex nature of the abdominal aortic aneurysm geometry, the physiological forces and constraints acting on the abdominal aortic aneurysm wall were measured by using a simulation setup using boundary conditions and initial conditions for different studies such as finite element analysis or computational fluid dynamics. RESULTS: The flow pattern showed an increase velocity at the angular neck, followed by a stagnated flow inside the aneurysm sack. Furthermore, the wall shear stress analysis showed to focalized points of higher stress, the top and bottom of the aneurysm sack, where the flow collides against the wall. An increase of the viscosity showed no significant velocity changed but results in a slight increase in overall pressure and wall shear stress. CONCLUSIONS: Conducting computational fluid dynamics modeling of the abdominal aortic aneurysm using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA) proves to be an insightful approach for the clinical setting. The careful consideration of the biomechanics of the abdominal aortic aneurysm may lead to an improved, case-specific prediction of the abdominal aortic aneurysm rupture potential, which could significantly improve the clinical management of these patients.
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González-Urquijo et al. (2021) studied Abdominal aortic aneurysm. 3D computational fluid dynamics modeling was evaluated on Flow pattern and wall shear stress. 3D computational fluid dynamics modeling of a simulated abdominal aortic aneurysm demonstrated increased velocity at the angular neck and focalized high wall shear stress at the top and bottom.
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