Answers are grounded in this paper and cite their sources.
Two types of diblock copolymers containing phenylboronic acid and glucose moieties, respectively, poly(N-isopropylacrylamide)-b-poly(N-acryloyl-3-aminophenylboronic acid) (PNIPAM-b-PAPBA) and poly(Nisopropylacrylamide)- b-poly(acryloyl glucosamine) (PNIPAM-b-PAGA) were synthesized via reversible additionfragmentation chain transfer (RAFT) polymerization. Due to the formation of borate ester functionalities between phenylboronic acid and glucose moieties under slightly alkaline conditions (pH 9.3), mixed solution of PNIPAM-b-PAPBA and PNIPAM-b-PAGA diblock copolymers can spontaneously form interpolymer complex micelles consisting of PAPBA/PAGA complex cores and PNIPAM coronas. Since the formation/cleavage of borate ester linkages is highly reversible upon the variation of solution pH and glucose concentrations, interpolymer complex micelles fabricated via reversible covalent bond formation between PAPBA and PAGA blocks exhibit multi-responsiveness to pH, glucose and temperature.
No takes yet. Share an insight, caveat, or question.
LIU et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: