Answers are grounded in this paper and cite their sources.
A regio- and stereoselective migration takes place under mild conditions for tertiary organoboranes obtained by hydroboration of tetrasubstituted cyclic alkenes. A subsequent amination proceeds with perfect control of the stereochemistry. The scheme shows an example of this for the reaction of bicyclo[4.3.0]non-1(6)-ene (1) to 2 via intermediates 3 and 4. Compound 2 is formed as the single diastereomer in 69% yield.
No takes yet. Share an insight, caveat, or question.
Lhermitte et al. (1998) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: