Answers are grounded in this paper and cite their sources.
A novel palladium‐catalyzed CH double carbonylation introduces two adjacent carbonyl groups for the synthesis of isatins from readily available anilines. The reaction proceeds under atmospheric pressure of CO with high regioselectivity and without any additives. Density functional theory investigations indicate that the palladium‐catalyzed double carbonylation catalytic cycle is plausible.
No takes yet. Share an insight, caveat, or question.
Li et al. (2014) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: