Key result
Lipid-lowering therapy reaches only ~42% of Aboriginal and Torres Strait Islander adults at high CVD risk.
Why the study?
Absolute cardiovascular disease risk and use of lipid-lowering therapies among Aboriginal and Torres Strait Islander people were not well quantified nationally.
Cross-Sectional (n=2,820)
Yes
Aboriginal and Torres Strait Islander people have high absolute CVD risk, including substantial proportions under 35 years, yet most at high risk are undertreated with lipid-lowering therapy.
Undertreatment with lipid-lowering therapy may persist in high-risk Aboriginal and Torres Strait Islander adults; leaves open whether targeted interventions improve uptake and outcomes.
OBJECTIVE: To quantify absolute cardiovascular disease (CVD) risk in Aboriginal and Torres Strait Islander people and their use of lipid-lowering therapies. DESIGN, PARTICIPANTS: Cross-sectional analysis of nationally representative data from 2820 participants aged 18-74 years who provided biomedical data for the National Aboriginal and Torres Strait Islander Health Measures Survey component of the 2012-13 Australian Aboriginal and Torres Strait Islander Health Survey. MAIN OUTCOME MEASURES: Prior CVD and use of lipid-lowering medications were ascertained at interview. 5-year absolute risk of a primary CVD event was calculated with the Australian National Vascular Disease Prevention Alliance algorithm, with categories low (< 10%), moderate (10-15%) and high risk (> 15%). RESULTS: Among participants aged 35-74 years, 9.6% (95% CI, 7.2-12.0%) had prior CVD; 15.7% (95% CI, 13.0-18.3%) were at high, 4.9% (95% CI, 3.3-6.6%) at moderate, and 69.8% (95% CI, 66.8-72.8%) at low absolute primary CVD risk. 82.6% of those at high primary risk were identified on the basis of clinical criteria. High primary absolute risk affected 1.1% (95% CI, 0.0-2.5%) of 18-24-year-olds, 4.7% (95% CI, 2.0-7.5%) of 25-34-year-olds, and 44.2% (95% CI, 33.1-55.3%) of 65-74-year-olds. Lipid-lowering therapy was being used by 52.9% (95% CI, 38.2-67.6%) of people aged 35-74 years with prior CVD and by 42.2% (95% CI, 30.5-53.8%) of those at high primary CVD risk. CONCLUSION: Absolute CVD risk is high among Aboriginal and Torres Strait Islander people, and most of those at high risk are undertreated. Substantial proportions of people under 35 years of age are at high risk, but are not targeted by current guidelines for absolute CVD risk assessment, compromising CVD prevention in this population.
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Calabria et al. (2018) conducted a cross-sectional in Cardiovascular disease risk (n=2,820). High absolute CVD risk was evaluated on 5-year absolute risk of a primary CVD event and use of lipid-lowering medications. Among Aboriginal and Torres Strait Islander people aged 35-74 years, 15.7% were at high absolute primary CVD risk, and only 42.2% of these high-risk individuals used lipid-lowering therapy.
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