Key result
In patients with dilated cardiomyopathy, ICD/CRT-D implantation was associated with a sudden cardiac death rate of 1.6% compared to 2.8% in patients without an ICD (difference not significant).
Why the study?
To evaluate the efficacy of ICDs in sudden cardiac death prevention and overall mortality, identify predictors of appropriate shocks, and refine risk stratification in dilated cardiomyopathy.
Does ICD/CRT-D implantation reduce sudden cardiac death and mortality in patients with dilated cardiomyopathy?
Cohort (n=293)
Does ICD/CRT-D implantation reduce sudden cardiac death and mortality in patients with dilated cardiomyopathy?
In patients with dilated cardiomyopathy, ICD/CRT-D did not significantly reduce total mortality, but primary/genetic etiology and sustained VT were identified as predictors of appropriate shocks.
Does not support changing ICD indications in dilated cardiomyopathy; hypothesis-generating and requires randomized confirmation.
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Solovyeva et al. (2020) conducted a cohort in Dilated cardiomyopathy syndrome (n=293). Implantable cardioverter-defibrillator (ICD/CRT-D) vs. No ICD was evaluated on Sudden cardiac death. In patients with dilated cardiomyopathy, ICD/CRT-D implantation was associated with a sudden cardiac death rate of 1.6% compared to 2.8% in patients without an ICD (difference not significant).
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