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SummaryDiethylpropion (‘Tenuate Dospan’) was found to be an acceptable therapy when given on a long-term basis to 20 very overweight patients who had failed to lose weight on diet alone. There were remarkably few untoward side-effects and no indication of the development of tolerance to the drug. An interesting feature of the trial was a correlation between fall in blood pressure with loss of weight.
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R. H.G. McKay (1973) studied this question.