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May 1, 2000Archives of Biochemistry and BiophysicsOpen Access

Arsenic Inhibits NF-κB-mediated Gene Transcription by Blocking IκB Kinase Activity and IκBα Phosphorylation and Degradation

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Authors

RRRobert R. RousselUnited States Army Medical CommandABAaron BarchowskyUniversity of Pittsburgh

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Roussel et al. (2000) studied this question.

synapsesocial.com/papers/6aa930bde4c74ea018878af8https://doi.org/10.1006/abbi.2000.1770
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IκB: a Specific Inhibitor of the NF-κB Transcription Factor1988 · 2,188 citations
  2. 2Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.1993 · 967 citations
  3. 3IκB Kinases: Kinsmen with Different Crafts1999 · 125 citations
  4. 4IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK1997 · 1,189 citations
  5. 5Cell Stress and MKK6b-mediated p38 MAP Kinase Activation Inhibit Tumor Necrosis Factor-induced IκB Phosphorylation and NF-κB Activation1999 · 97 citations