Management of the aortic arch in patients with syndromic heritable thoracic aortic disease

Figures

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  Figure 1:. Flowchart depicting the MFS cohort. Patients are divided by initial presentation in elective (A) and dissection; type A (B) and type B AAD (C) (see text for details). AAD: acute aortic dissection; MFS: Marfan syndrome; PAR: partial arch replacement; TAAA: thoracoabdominal replacement (open or TEVAR); TAR: total arch replacement

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  Figure 2:. Flowchart depicting the LDS cohort. Patients are divided by initial presentation in elective (A) and dissection (B) (see text for details). AAD: acute aortic dissection; MFS: Marfan syndrome; LDS: Loeys–Dietz syndrome; PAR: partial arch replacement; TAAA: thoracoabdominal replacement (open or TEVAR); TAR: total arch replacement

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  Figure 3:. Kaplan–Meier plots for freedom from secondary TAR between MFS patients with aortic dissection and MFS patients without aortic dissection prior to aortic arch replacement. There was significantly more secondary TAR in MFS patients with aortic dissection compared to MFS patients without aortic dissection. TAR: total arch replacement

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  Figure 4:. Summarizing the 52 patients and the aortic segments that were treated before and after aortic arch replacement. Each line represents one patient. LDS: Loeys–Dietz syndrome; MFS: Marfan syndrome

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  Figure 5:. Kaplan–Meier plots for freedom from downstream aortic events between MFS patients with secondary TAR and MFS patients with partial arch replacement. There was no increased probability for downstream aortic events in MFS patients with secondary TAR compared to MFS patients with partial arch replacement. Downstream aortic events: new type B aortic dissection, open thoracoabdominal replacement, thoracic endovascular aortic repair, endovascular aneurysm repair, abdominal aortic replacement

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  Figure 6:. Kaplan–Meier survival plots. All-cause mortality did not differ between MFS patients with and without secondary TAR